Can cause digestive issues and discomfort such as bloating, gas, diarrhea, and stomach pain in some people, especially in large quantities. Another concern with erythritol is its impact on blood sugar and insulin levels. While erythritol does not have a significant effect on blood sugar or insulin levels in healthy people, some research suggests that it may be problematic for those with insulin resistance or diabetes. There are also some concerns about the safety of erythritol over the long term. While erythritol has generally been recognized as safe by regulatory bodies like the FDA, some animal studies have suggested that it may have negative effects on the kidneys and liver.